Publications

ORCID #0000-0001-7744-3238
Google Scholar

Journal Articles (Peer-reviewed)

PF Chinnery, M Bonnet, A Cave, MP Hofer, A Lamb, GA McConkey, … Choosing drugs for UK COVID-19 treatment trials Nature Reviews Drug Discovery 2021

Targeting Oncogenic Micrornas in Malignant Germ Cell Tumours with Locked Nucleic Acid (LNA)-Based Inhibitors S Bailey, M Ferraresso, S Smith, D Ward, JC Nicholson, A Enright, N Coleman, M Murray* PEDIATRIC BLOOD & CANCER 68, S148-S149 2021

IJ Groves, ELA Drane, M Michalski, JM Monahan, CG Scarpini, SP Smith, … Short- and long-range cis interactions between integrated HPV genomes and cellular chromatin dysregulate host gene expression in early cervical carcinogenesis PLoS pathogens 17 (8), e1009875 4* 2021

A Shapanis, C Lai, S Smith, G Coltart, M Sommerlad, J Schofield, … Identification of proteins associated with development of metastasis from cutaneous squamous cell carcinomas (cSCCs) via proteomic analysis of primary cSCCs British Journal of Dermatology 184 (4), 709-721

S.B. Hasan, S.P. Smith, A. Brain, M.F. Mohd Mustapa, S.T. Cheung, J.R. Ingram and D.A.R. de Berker
British Association of Dermatologists (BAD) National Clinical Audit on the Management of Hidradenitis Suppurativa (HS) in the UK
Clinical and Experimental Dermatology 2021 DOI: 10.1111/ced.14598

S.P. Smith, E. Nagore, R. Kumar, R. Marais, C. Gaudy-Marqueste, A. Virós
Genetic markers of prognosis and immunotherapy response in melanoma of the elderly.
BioarXiv 2021

I.J. Groves, E.L.A. Drane, M. Michalski, J. Monahan, C.G. Scarpini, S.P. Smith, G. Bussotti, C. Varnai, S. Schoenfelder, P. Fraser, A.J. Enright, N. Coleman
Three-dimensional interactions between integrated HPV genomes and cellularchromatin dysregulate host gene expression in early cervical carcinogenesis.
BioarXiv 2021

S. Goncalves, K. Yin, Y. Ito, A. Chan, I. Olan, S.P. Smith, A. Young, M. Narita, M. Hoare
COX2 regulates senescence secretome composition and senescence surveillance through PGE2.
Cell reports 2021. Accepted for publication.

M.J. Murray, S.P. Smith, D. Ward, L. Verduci , J.C. Nicholson, C.G. Scarpini, N. Coleman
Circulating microRNAs as biomarkers to assist the management of the malignant germ-cell-tumour subtype choriocarcinoma.
Translational Oncology 2020, Volume 14, Issue 1, 100904; https://doi.org/10.1016/j.tranon.2020.100904

A Shapanis, C. Lai, S.P. Smith, G Coltart, M. Sommerlad, J. Schofield, E Parkinson, P. Skipp, E. Healy
Identification of proteins associated with development of metastasis from cutaneous squamous cell carcinomas (cSCCs) via proteomic analysis of primary cSCCs.
British Journal of Dermatology 13 August 2020 https://doi.org/10.1111/bjd.19485

Smith SP, Mohd Mustapa MF, de Berker D.
The landscape of psoriasis provision in the UK.
Clinical and Experimental Dermatology 2020;10.1111/ced.14286. https://doi:10.1111/ced.14286

Pellagatti A, Steeples V, Armstrong RN, Sharma E, Repapi E, Singh S, Sanchi A, Radujkovic A, Horn P, Dolatshad H, Roy S, Lockstone H, Taylor S, Giagounidis A, Vyas P, Schuh A, Hamblin A, Papaemmanuil E, Killick S, Malcovati L, Gavin A-C, Ho AD, Luft T, Hellström-Lindberg E, Cazzola M, Smith CWJ, Smith SP, and Boultwood J
Impact of spliceosome mutations on RNA splicing in myelodysplasia: dysregulated genes/pathways and clinical associations.
Blood 2018 Jun 21. 132 (12): 1225–1240. https://doi.org/10.1182/blood-2018-04-843771

Parry AJ, Hoare M, Bihary D, Hänsel-Hertsch R, Smith SP, Tomimatsu K, Mannion E, Smith A, D’Santos P, Russell IA, Balasubramanian S, Kimura H, Samarajiwa SA & Narita M
NOTCH-mediated non-cell autonomous regulation of chromatin structure during senescence.
Nature Communications May 2018 volume 9, Article number: 1840 (2018) https://doi.org/10.1038/s41467-018-04283-9

Kucia‐Tran, J. A., Tulkki, V. , Scarpini, C. G., Smith, S.P. , Wallberg, M. , Paez‐Ribes, M. , Araujo, A. M., Botthoff, J. , Feeney, M. , Hughes, K. , Caffarel, M. M. and Coleman, N.
Anti‐oncostatin M antibody inhibits the pro‐malignant effects of oncostatin M receptor overexpression in squamous cell carcinoma.
Journal of Pathology, Jan. 2018 244: 283-295. https://doi.org/10.1002/path.5010

Smith SP, Baxendale HE, Sterling JC.
Therapeutic use of the quadrivalent Human Papillomavirus vaccine for recalcitrant warts in idiopathic immune deficiency.
Clinical and Experimental Dermatology Jan 2017 42: 306-308. https://doi.org/10.1111/ced.13038

Smith SP, Scarpini CG, Groves IJ, Odle RI, Coleman N
Identification of host transcriptional networks showing concentration-dependent regulation by HPV16 E6 and E7 proteins in basal cervical squamous epithelial cells.
Scientific Reports Jul 2016; 6:29832. https://doi.org/10.1038/srep29832

Kucia J, Tulkki V, Smith SP, Scarpini C, Hughes K, Araujo AM, Yan KYM, Botthof J, Prez-Gmez E, Sanchez C, Quintanilla M, Cuschieri K, Caffarel MM, Coleman N
Overexpression of the oncostatin M receptor in cervical squamous cell carcinoma is associated with epithelialmesenchymal transition and increased metastasis.
British Journal of Cancer Jul 2016; 115(2):212–22. https://doi.org/10.1038/bjc.2016.199

Raffan E, Dennis R, O’Donovan C, Becker J, Scott R, Smith SP, Withers D, Wood C, Conci E, Clements D, Summers K, German A, Mellerch C, Arendt M, Iyemere V, Withers E, Soder J, Wernersson S, Andersson G, Lindlad-Toh K, Yeo G, O’Rahilly SO
A deletion in the canine POMC gene and its relationship to the obesity-proneness of Labrador retriever dogs.
Cell Metabolism 2016 May; 23(5): 893–900. https://dx.doi.org/10.1016/j.cmet.2016.04.012

Raffan E, Smith SP, O’Rahilly SO, Wardle J.
Development, factor structure and application of the Dog Obesity Risk and Appetite (DORA) questionnaire.
PeerJ 2015; 3:e1278; https://doi.org/10.7717/peerj.1278

Smith SP, Crawley C, See TC, Screaton N and Preller J.
A case of BK virus causing bilateral ureteric obstruction in an allogeneic stem cell transplant recipient.
Journal of Clinical Virology 2013 Jan; 56(1): 1-4. https://doi.org/10.1016/j.jcv.2012.07.003

Published Abstracts

Bailey S, Ferraresso M, Smith SP, Nicholson JC, Scarpini CG, Enright AJ, Murray MJ, Coleman N.
Targeting oncogenic microRNAs in malignant germ cell tumours with locked nucleic acid-based inhibitors.
European Urology Supplements 2019; 18 (4) 22

Ferraresso M, Bailey S, Panayi C, Smith SP, Nicholson JC, Scarpini CG, Enright AJ, Coleman N, Murray MJ.
Mechanism and functional significance of downregulated microRNA expression in malignant germ cell tumours.
European Urology Supplements 2019; 18 (4) 22

Smith SP, Amin K, Fang S, Morrison T, Coleman N, Murray MJ, Enright AJ.
Analysing large scale TGCT data from The Cancer Genome Atlas (TCGA): Challenges and considerations.
European Urology Supplements 2019; 18 (4) 38

Hasan H, Smith SP, Scarpini CG and Coleman N.
Human papillomavirus subversion of host RNA splicing machinery in early progression.
British Journal of Dermatology 2019; 181 (S1) 48

Smith S.P., Gaudy-Marqueste C, Kumar R, Marais R, Nagore E, Viros A.
Genomic characterization of melanoma in the elderly reveals molecular drivers of progression and prognosis associated with immunotherapy response
Cancer Research 2019; 79 (13 Supplement) 3994-3994; https://DOI.org/10.1158/1538-7445.AM2019-3994

Nagore E, Roeck K, Budden T, Smith SP, Craig S, Krutmann J, Lotz M, Furney S, Viros A.
Chronic UV damage of the stroma improves melanoma survival
Cancer Research 2019; 79 (13 Supplement) 2022-2022; https://DOI.org/10.1158/1538-7445.AM2019-2022

S.P. Smith
1067 Fascin and Cdk2 are synthetic lethal partners with exceptional potential as joint therapeutic targets in malignant melanoma
Journal of Investigative Dermatology 2018; 138 (5), S181 https://doi.org/10.1016/j.jid.2018.03.1080

Smith SP, Mehta SG, Burrows N.
A Rare Form of Classical Ehlers-Danlos Syndrome with Arterial Rupture.
British Journal of Dermatology 2016; Online Supplement (Accepted)

Raffan E, Smith SP, Wardle J, O’Rahilly S,
Variation in appetitive behaviour between pet dogs; association with obesity and relationship to owner management factors.
Journal of Veterinary Behavior: Clinical Applications and Research 2015; 10 (5), 447, https://doi.org/10.1016/j.jveb.2015.07.032.

Raffan E, Diss S, Smith SP, Wardle J
Development and validation of the Dog Obesity Risk and Appetite (DORA) questionnaire
Acta Veterinaria Scandinavica 2015, 57(Suppl 1):O18

Smith SP.
Network analysis identifies master regulators of metastasis in cutaneous melanoma.
British Journal of Dermatology 2015 July; 173 (S1): 2176. https://doi.org/10.1111/bjd.13761

Smith SP
Bioinformatics Identification of Personalised Medicine Repositioning Candidates in Atopic Dermatitis.
Clinical and Experimental Dermatology 2015; Online Supplement

Smith SP, Tate S, Collie DD.
Interleukin 10 is upregulated in Contralateral Lung Segments Following Local LPS Challenge.
Proceedings of the 42nd IDSA Congress 2004

Books

Co-editor: BMA New Guide to Medicines and Drugs. (2015)